Antioxidant Defense: Nrf2 activation leads to the upregulation of various antioxidant enzymes, such as superoxide dismutase (SOD), catalase, and glutathione peroxidase. This helps to combat oxidative stress induced by intense physical exercise, reducing muscle damage and promoting faster recovery.
Athletic and Performance Benefits

What Happens when Athletes ACTIVATE?
Athletes have higher Oxidative Stress
For many of us, exercise is a normal part of our everyday routine. Many of us do so for the health benefits like stress relief, weight management, increased energy levels and reduced risk of health conditions. Others focus more on the performance benefits such as getting stronger, faster, or more skilled at a specific activity.
Unfortunately there’s a catch – too much of a good thing can turn into a bad thing. Increased amounts of high-intensity, prolonged and/or strenuous exercise leads to a large rise in free radicals which exceeds the protective capacity of our defense system.
When this happens, free radicals are left unattended and are able to damage our cells which leads to cellular damage, or a condition known as oxidative stress.

Activation can improve your performance
Oxidative stress not only has the potential to disrupt your overall health, it also has the ability to negatively impact your performance.
Specifically, active individuals with high levels of oxidative stress are likely to be more fatigued and have more muscle soreness – two things that can lengthen recovery time.

How do you ACTIVATE? The Tri-Synergizer
Protandim NRF2
You can protect against increasing free radical damage by naturally switching on the body’s internal defense systems with Protandim Nrf2 Synergizer.
Protandim Nrf2 activator increases levels of antioxidant enzymes (superoxide dismutase, catalase, and glutathione). Benefits include:
- Decreases Oxidative Stress 40% in 30 days
- Potentially reducing levels of fatigue and muscle soreness associated with longer recovery times and
- Supporting peak performance during each training session which would allow for the greatest benefits of exercise to be achieved.


Protandim NRF1
Your body’s energy and performance start with mitochondria. But mitochondria decline with age or when stressed. Protandim NRF1 activates the NRF1 pathway, which is responsible for mitochondrial health.
Mitochondria are your power generators, and Protandim NRF1 creates more of them and provides the nutrients they need immediately. Benefits include:
- Increases adenosine triphosphate (ATP), your cellular energy
- Improves performance through energy function
- optimizes your body’s ability to boost mitochondria function
Protandim NAD
Get a boost for your energy, focus, and mood—while you support your total health and longevity.
Protandim NAD is specifically formulated to activate important proteins called sirtuins. Sirtuins deliver whole-body benefits, such as support for healthy longevity, the body’s healthy inflammatory response, joint health, a healthy vascular system, and more.
- Doubles sirtuin activity in 24 hours
- Supports healthy longevity and the removal of cellular waste (autophagy)
- Supports the body's healthy inflammatory response
- Maintain existing healthy cholesterol levels and supports healthy vascular system


Increase Glutathione 300%
THE “MOST POWERFUL ANTIOXIDANT” FOR YOUR BODY
Glutathione is the body’s essential health ABC’s – Antioxidant, Blood Booster and Cell Detoxifier.This small protein, produced naturally in the body, maintains these three crucial protective functions.
Glutathione is always in great demand and is rapidly consumed when we experience any sort of emotional or physical stress, fatigue and even moderate exercise.
Glutathione is also important to physically active people. Many world-class athletes are discovering that well-maintained glutathione levels gives them the edge over their competitors, bringing greater strength and endurance, decreased recovery time from injury, less muscle pain and fatigue, and muscle-promoting activity.
As an essential aid to health, glutathione works as the master antioxidant in our body, optimizes the white blood cells and detoxifies a long list of pollutants and carcinogens or acids.

A Study conducted by the University of Colorado Denver showed:
Protandim produces a 300% increase in the cellular production of glutathione. As a key antioxidant, glutathione plays critical roles in the regensis of other antioxidants (Vitamins C and E), liver detoxification and elimination, and tissue repair.
Improve Focus and Concentration
Nootropic - Better Concentration and Energy
Get motivated with AXIO Smart Energy nootropic supplement. You get a targeted blend of vitamins, minerals, and phytonutrients that support energy metabolism—without unwanted calories or sugar. While AXIO gives you instant energy, it also delivers other benefits, such as support for your body’s response to everyday stress. Wake up your brain, nourish your body, and get the right kind of energy, right when you need it, without the jitters or caffeine crash.
- Improves mental endurance & mental acuity, concentration & memory retention
- Increases physical & mental energy while improving positive mood
- Supports neurotransmitter function and the brain’s resilience to stress
- Reduces mental fatigue & brain fog
- Clean, low-calorie, low-carb, vegetarian formula, BSCG approved and free of artificial colors, artificial flavors, artificial sweeteners, added sugars, GMOs and gluten
AXIO Smart Energy nootropic supplement comes in a variety of flavors and also in decaf form.
For Athletes and Mathletes


Tested and Certified by the BSCG
THE GOLD STANDARD IN CERTIFICATION AND TESTING
BSCG offers a complete suite of certification, testing and GMP compliance services to the dietary supplement and natural product industries. With a foundation in anti-doping and sport drug testing, BSCG offers the Olympic standard in analytical testing to finished product brands, ingredient suppliers, manufacturing facilities, teams, leagues, athletes or other consumers that want to verify that the quality of products and ingredients meet expectations and ensure they are not contaminated with drugs or other agents that can lead to health concerns or positive drug tests. The certification programs we offer are highlighted below, please contact us for more details.
BSCG Certified Drug Free® provides protection against drugs on the World Anti-Doping Agency (WADA) Prohibited List as well as, prescription, over-the-counter (OTC), and illicit drugs not banned in sport.

LifeVantage products popular with athletes are BSCG certified including:
- Protandim Nrf2 Synergizer
- Protandim NRF1 Synergizer
- Protandim NAD Synergizer
- Axio Regular and Decaf
What are personal trainers saying?
What are athletes saying?
Jessica Crate
Olympic Level Elite Marathon runner
Nick Baumgartner
World Champion Snowboarder
Simon Kessler
Professional Cyclist
Aubrey Huff
2 Time MLB World Series Champion
Luke Mulholland
Former Major League Soccer Star

Kelly Slater - 11x World Champion Surfer
"I've been on it for years now and can attest to the power of this product in helping to recover, besides just feeling so good now. I will NEVER not take it!”

Anthony Robles - One-legged wrestler who won the 2011 NCAA 125-pound title and long-time LifeVantage consumer - broke the world record for pull-ups in a single minute. "I have been taking Protandim since 2012."

Ozzie Newsome - NFL Pro Football Hall of Famer - "I have been taking Protandim for years. My workouts have become stronger, longer and more intense. I will never miss a day of taking it."

Grandmaster Joseph Kim - 2 Time Olympic Gold Medalist and NFL Asst. Coach
"Protandim has helped my endurance. My recovery is unbelievable. I believe in the science and I feel 20 years younger."



